Tropomodulin Protects a-Ca
نویسندگان
چکیده
Elisabeth A. Cox-Paulson,1 Elise Walck-Shannon,2 Allison M. Lynch,3 Sawako Yamashiro,4,5 Ronen Zaidel-Bar,3,6 Celeste C. Eno,2 Shoichiro Ono,4 and Jeff Hardin2,3,* 1Department of Biology, State University of New York at Geneseo, 353 Integrated Science Center, 1 College Circle, Geneseo, NY 14454, USA 2Program in Genetics, University of Wisconsin–Madison, 1117 W. Johnson Street, Madison, WI 53706, USA 3Department of Zoology, University of Wisconsin–Madison, 1117 W. Johnson Street, Madison, WI 53706, USA 4Department of Pathology, Emory University, Whitehead Research Building, Room 105N, Atlanta, GA 30322, USA
منابع مشابه
Tropomodulin Protects α-Catenin-Dependent Junctional-Actin Networks under Stress during Epithelial Morphogenesis
α-catenin is central to recruitment of actin networks to the cadherin-catenin complex, but how such networks are subsequently stabilized against stress applied during morphogenesis is poorly understood. To identify proteins that functionally interact with α-catenin in this process, we performed enhancer screening using a weak allele of the C. elegans α-catenin, hmp-1, thereby identifying UNC-94...
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Many proteins have been shown to cap the fast growing (barbed) ends of actin filaments, but none have been shown to block elongation and depolymerization at the slow growing (pointed) filament ends. Tropomodulin is a tropomyosin-binding protein originally isolated from red blood cells that has been localized by immunofluorescence staining to a site at or near the pointed ends of skeletal muscle...
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تاریخ انتشار 2012